1: Valerian Root:
Leathwood PD, Chauffard F. Aqueous extract of valerian reduces latency to fall asleep in man. Planta Med. 1985;(2):144-8.
Balderer G, Borbély AA. Effect of valerian on human sleep. Psychopharmacology (Berl). 1985;87(4):406-9.
Bent S, Padula A, Moore D, Patterson M, Mehling W. Valerian for sleep: a systematic review and meta-analysis. Am J Med. 2006;119(12):1005-12.
2: Passion Flower:
0Li H, Zhou P, Yang Q, Shen Y, et al. Comparative studies on anxiolytic activities and flavonoid compositions of Passiflora edulis ‘edulis’ and Passiflora edulis ‘flavicarpa’. J Ethnopharmacol. 2011 Feb 16;133(3): 1085-90.
Akhondzadeh, Shahin, H. R. Naghavi, M. Vazirian, A. Shayeganpour, H. Rashidi, and M. Khani. “Passionflower in the treatment of generalized anxiety: a pilot double‐blind randomized controlled trial with oxazepam.”Journal of Clinical Pharmacy and Therapeutics 26, no. 5 (2001): 363-367.
Ngan A, Conduit R. A double-blind, placebo-controlled investigation of the effects of Passiflora incarnata (passionflower) herbal tea on subjective sleep quality. Phytother Res. 2011 Aug;25(8):1153-9.
Arangino S, Cagnacci A, Angiolucci M, et al. Effects of melatonin on vascular reactivity, catecholamine levels, and blood pressure in healthy men. Am J Cardiol. 1999;83(9):1417-9.
Nishiyama K, Yasue H, Moriyama Y, et al. Acute effects of melatonin administration on cardiovascular autonomic regulation in healthy men. Am Heart J. 2001;141(5):E9.
Dubocovich ML. Melatonin receptors: role on sleep and circadian rhythm regulation. Sleep Med. 2007;8 Suppl 3:34-42.
Eby GA, Eby KL. Magnesium for treatment-resistant depression: a review and hypothesis. Med Hypotheses. 2010;74(4):649-60.
Hatzistavri LS, Sarafidis PA, Georgianos PI, et al. Oral magnesium supplementation reduces ambulatory blood pressure in patients with mild hypertension. Am J Hypertens. 2009;22(10):1070-5.
Kawano Y, Matsuoka H, Takishita S, Omae T. Effects of magnesium supplementation in hypertensive patients: assessment by office, home, and ambulatory blood pressures. Hypertension. 1998;32(2):260-5.
Kenta Kimura, Makoto Ozeki, Lekh Raj Juneja, Hideki Ohira, -Theanine reduces psychological and physiological stress responses, Biological Psychology, Volume 74, Issue 1, 2007, Pages 39-45,
Sleep in Children With Attention-Deficit/Hyperactivity Disorder: Meta-Analysis of Subjective and Objective Studies Cortese, Samuele et al. Journal of the American Academy of Child & Adolescent Psychiatry , Volume 48 , Issue 9 , 894 – 908
Lekh Raj Juneja, Djong-Chi Chu, Tsutomu Okubo, Yukiko Nagato, Hidehiko Yokogoshi, L-theanine—a unique amino acid of green tea and its relaxation effect in humans, Trends in Food Science & Technology, Volume 10, Issue 6, 1999, Pages 199-204,
Franco L, Sánchez C, Bravo R, Rodriguez A, Barriga C, Juánez JC (2012). “The sedative effects of hops (Humulus lupulus), a component of beer, on the activity/rest rhythm”. Acta Physiol Hung. 99 (2): 133–9.
Schellenberg, R., Sauer, S., Abourashed, E. A., Koetter, U., and Brattstrom, A. The fixed combination of valerian and hops (Ze91019) acts via a central adenosine mechanism. Planta Med 2004;70(7):594-597
Hänsel R, Wohlfart R, and Schmidt H. The sedative-hypnotic principle of hops.
Communication: contents of 2-methyl-3-butene-2-ol in hops and hop preparations. Planta
7: Lemon Balm:
Dimpfel W, Pischel I, Lehnfeld R. Effects of lozenge containing lavender oil, extracts from hops, lemon balm and oat on electrical brain activity of volunteers. Eur J Med Res. 2004;9(9):423-31.
Cases J, Ibarra A, Feuillère N, Roller M, Sukkar SG. Pilot trial of Melissa officinalis L. leaf extract in the treatment of volunteers suffering from mild-to-moderate anxiety disorders and sleep disturbances. Med J Nutrition Metab. 2011;4(3):211-218.
Kennedy DO, Scholey AB, Tildesley NT, Perry EK, Wesnes KA. Modulation of mood and cognitive performance following acute administration of Melissa officinalis (lemon balm). Pharmacol Biochem Behav. 2002;72(4):953-64.
Mann C, Staba EJ. The chemistry, pharmacology, and commercial formulations of chamomile. In: Craker LE, Simon JE, eds. Herbs, Spices, and Medicinal Plants: Recent Advances in Botany, Horticulture, and Pharmacology, vol 1. Arizona: Oryx Press, 1986: 235–280. http://agris.fao.org/agris-search/search.do?recordID=US8700832
Sarris, J; Panossian, A; Schweitzer, I; Stough, C; Scholey, A (December 2011). “Herbal medicine for depression, anxiety, and insomnia: a review of psychopharmacology and clinical evidence”. European neuropsychopharmacology. 21 (12): 841–860. https://www.ncbi.nlm.nih.gov/pubmed/21601431
Patel, D., Shukla, S., & Gupta, S. (2007). Apigenin and cancer chemoprevention: Progress, potential and promise (Review). International Journal of Oncology, 30, 233-245. https://doi.org/10.3892/ijo.30.1.233 https://www.spandidos-publications.com/ijo/30/1/233
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Lodish HF. Molecular Cell Biology. W.H.Freeman & Co Ltd; 2008.
Eliot AC, Kirsch JF. Pyridoxal phosphate enzymes: mechanistic, structural, and evolutionary considerations. Annu Rev Biochem. 2004;73:383-415.
Shideler CE. Vitamin B6: an overview. Am J Med Technol. 1983;49(1):17-22.
2: Leucine Isoleucine Valine:
Gualano AB, Bozza T, Lopes de campos P, et al. Branched-chain amino acids supplementation enhances exercise capacity and lipid oxidation during endurance exercise after muscle glycogen depletion. J Sports Med Phys Fitness. 2011;51(1):82-8.
Vander haar E, Lee SI, Bandhakavi S, Griffin TJ, Kim DH. Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40. Nat Cell Biol. 2007;9(3):316-23.
Navé BT, Ouwens M, Withers DJ, Alessi DR, Shepherd PR. Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation. Biochem J. 1999;344 Pt 2:427-31.
Hankard RG, Haymond MW, Darmaun D. Effect of glutamine on leucine metabolism in humans. Am J Physiol. 1996;271(4 Pt 1):E748-54.
Hankard RG, Darmaun D, Sager BK, D’amore D, Parsons WR, Haymond M. Response of glutamine metabolism to exogenous glutamine in humans. Am J Physiol. 1995;269(4 Pt 1):E663-70.
Zhou X, Thompson JR. Regulation of protein turnover by glutamine in heat-shocked skeletal myotubes. Biochim Biophys Acta. 1997;1357(2):234-42.
4: Citrulline Malate:
Pérez-guisado J, Jakeman PM. Citrulline malate enhances athletic anaerobic performance and relieves muscle soreness. J Strength Cond Res. 2010;24(5):1215-22.
Bendahan D, Mattei JP, Ghattas B, Confort-gouny S, Le guern ME, Cozzone PJ. Citrulline/malate promotes aerobic energy production in human exercising muscle. Br J Sports Med. 2002;36(4):282-9.
Sureda A, Córdova A, Ferrer MD, Pérez G, Tur JA, Pons A. L-citrulline-malate influence over branched chain amino acid utilization during exercise. Eur J Appl Physiol. 2010;110(2):341-51.
5: Sodium Potassium Citrate:
Hew-butler T, Ayus JC, Kipps C, et al. Statement of the Second International Exercise-Associated Hyponatremia Consensus Development Conference, New Zealand, 2007. Clin J Sport Med. 2008;18(2):111-21.
Halperin ML, Kamel KS. Potassium. Lancet. 1998;352(9122):135-40.
Islam MR, Samadi AR, Ahmed SM, Bardhan PK, Ali A. Oral rehydration therapy: efficacy of sodium citrate equals to sodium bicarbonate for correction of acidosis in diarrhoea. Gut. 1984;25(8):900-4.